Herbalife ‘Scam’ Weight Loss Product Associated with Fatal Liver Failure
A case report from India has connected products from Herbalife to acute liver failure. The findings follow similar reports from other countries, including Israel, Spain, Switzerland, Iceland, Argentina and the United States. The study, published in the March-April issue of the Journal of Clinical and Experimental Hepatology, also points out the dangers associated with herbal and dietary supplements (HDSs), many of which promise results with no factual basis.
The case report highlights a 24-year-old woman with hypothyroidism who was otherwise healthy but taking thyroxine supplementation. She initiated three Herbalife products: Formula 1 Shake Mix (two scoops/day with skim milk), Personalized Protein Powder (two tablespoons twice/day into the Shake Mix), and Afresh Energy Drink (10 g twice/day).
Two months after starting these supplements, the patient had a week of lost appetite and then followed by jaundice and transient pruritus.
“Initial blood work revealed that total serum bilirubin level was12.4 (upper limit of normal [ULN] 1.1 mg/dL); direct bilirubin, 9.9 (ULN 0.2 mg/dL); aspartate aminotransferase,582 (ULN 36 U/L); alanine aminotransferase, 648 (ULN45 U/L); alkaline phosphatase, 248 (ULN 120 U/L);gamma-glutamyl transferase level, 398 (ULN 35 U/L); albumin, 3 (ULN 5.5 g/dL) and international normalised ratio,4.7 (normal 1.2),” the report details. When the patient’s jaundice worsened, she went to the emergency department. Blood tests were performed for conditions including hepatitis and HIV.
Check out a related article Hydroxycut and Garcinia Cambogia May Lead to Liver Failure
“A transjugular liver biopsy showed extensive periportal and perivenular bridging necrosis with moderate-to-severe mixed inflammatory infiltration, interface hepatitis, cholangitis, severe ballooning, steatosis and intracanalicular cholestasis,” according to the report. The patient was referred to a transplant center and placed on a waiting list but soon died.
An Assessment of Herbalife
The doctors considered the possibility that Herbalife had contributed to the patient’s liver injury but were unsuccessful in obtaining products from the patient’s grieving family, but they obtained one product from the same seller the patient purchased her products from—it was also discovered that this distributor was operating without a license and was eventually shut down by the Department of Health and Human Services, Government of Kerala. Other Herbalife products were purchased online.
Upon analysis, all of the sourced Herbalife products contained high levels of heavy metals, and 75% of the samples contained undisclosed toxic compounds, while 63% of the samples contained bacterial deoxyribonucleic acid. Upon RNA analysis, multiple bacterial communities were discovered in Herbalife products—“including highly pathogenic species.”
Health Supplements Likely Do More Harm than Good
The researchers pointed out that many products advertised as nutritional supplements based in wellness not only have no health benefits but could in fact be harmful. Often, these products boast potential outcomes with no clinical evidence to support the company’s claims.
“As with any drug, it is important to put HDSs through preclinical and clinical scientific studies and postmarketing vigilance so that unknown and potentially harmful causes for severe adverse effects, such as liver failure due to the use of such agents, may be more identifiable and controlled,” the researchers wrote.